Genotype Verification
Breeders Assistant can detect when the genotype of an individual is inconsistent with that of its parents.
Consider a gene 'A' that has two alleles 'A' and 'a'. If an individual is stated as having two 'a' alleles (i.e. is 'aa') then it is not possible for either parent to be 'AA'. Breeders Assistant can detect such errors - both at the time of entering an animal's genotype but also as part of a genetic verification of all individuals in a database.
E.g. with pedigreed cats it isn't possible for a Blue Point Siamese to be bred from a Seal Pt unless that Seal Pt is carrying blue. Restated in genetic notation, a cat thats blue (bb) cannot be bred from a sire or dam that is homozygous seal (BB). The seal parent(s) would have to be carrying blue (Bb).
Breeders Assistant also understands about sex-linked inheritance. E.g. in dogs, conditions such as Cerebellar Ataxia and the various forms of Haemophilia are sex linked. The dam of a male haemophiliac must either have haemophilia herself or (more likely) be a carrier, because it is carried on the X chromosome which males only inherit maternally. BA knows this. Yet another example of this is with inheritance of red(orange) in cat color genetics.
See Also:
Genetics Overview
Entering Genotypes
Comprehensive Cat Genetics
Comprehensive Dog Genetics
Inbreeding & Common Ancestors
Polygenic Inheritance Modelling
Mating Predictions
Gene Inheritance Probabilities
Genetic Configuration Files
Covariance Analysis
Gene Frequency Analysis
This feature requires the Genetics Option.
