Advanced Genetics

This page describes some features that are only present in the Professional and Commercial Editions of Breeders Assistant.

Genotype (Color) Prediction

All editions of Breeders Assistant include fields in which to store genotypes. These fields are found on the Genotype tab of the animal details window.

E.g. a dog breeder might enter Bb Dd in the Color Genotype field for a dog that carries liver/chocolate (Bb) and blue (Dd).

The Personal Edition of Breeders Assistant treats these fields much as any other - text fields that can be included in pedigrees etc. but otherwise no special significance is attached to them.

Trial Mating Pedigree, 4G with Genotype Predictions
Trial Mating Pedigree, 4G with Genotype Predictions
[Hi Res]

 

Mating Certificate with Genotype Predictions
Mating Certificate with Genotype Predictions

With the Professional Edition, and depending on your version of Breeders Assistant (see below), you can select a 'genetic configuration' which gives the program some intelligence about these fields:

  • It provides a friendlier way to enter the genotypes. Instead of just manually keying them into the boxes, you can now choose the disposition of each gene using pulldown menus, for example:
    Genotype Selection Pulldown
  • It can use the genotypes to make predictions as to the outcomes of matings. Many breeders know that the colors/patterns of the offspring from any given mating depend on the color genotype of the parents. If you know those genotypes, you can systematically work out the possibilities the mating will give rise to, and hence the distribution of colors/patterns that can theoretically be expected. You can get Breeders Assistant to do this for you instead of by hand, and you can include the results of such an analysis in a trial mating pedigree (like this) or a mating certificate1 (like this).

The genetic configurations that are available depend on which version of BA you get. Note that for those versions where we do not provide a genetic configuration for your breed/species, it is still possible for you to use the intelligent genotype facilities but you would need to create a genetic configuration yourself. Instructions for doing this are included in the BA help file.

The following table lists that standard genetic configurations that are currently supplied with the different versions of Breeders Assistant. They are provided as fixed configurations that cannot be user edited. Advanced users may like to know that it is possible to purchase these configurations in a user-modifiable format - for details please contact the Customer Service Help Desk.

Breeders Assistant Version Available Genetic Configurations
Breeders Assistant for Cats

Abyssinian, American Curl, American Shorthair, American Wirehair, Angora, Balinese and Javanese, Bengal, Birman, Bombay and Asian, British Shorthair, Burmese, Burmilla, Colourpoint, Cornish Rex, Devon Rex, Egyptian Mau, Foreign White, Havana Brown, Japanese Bobtail, Maine Coon, Manx and Cymric, Norwegian Forest Cat, Oriental Longhair, Oriental Shorthair, Persian, Ragdoll, Scottish Fold, Selkirk Rex, Siamese, Siberian, Singapura, Somali, Sphynx, Tiffanie, Tonkinese and Turkish Van.

In addition we also supply a generic configuration for use with other breeds and which uses a breed-independant nomenclature for the expressed colors.

For background information on feline colour genetics please see our cat colour genetics primer.

Breeders Assistant for Dogs

Afghan Hound, Akita, American Cocker Spaniel, Australian Shepherd, Basenji, Beagle, Border Collie, Boxer, Brittany, Bulldog, Chihuahua, Collie, Corgi, Dachshund, Dalmatian, Dobermann, Elkhound, English Cocker Spaniel, English Setter, English Springer Spaniel, Field Spaniel, Fox Terrier, Foxhound, French Bulldog, German Shepherd, Golden Retriever, Gordon Setter, Great Dane, Greyhound, Irish Setter, Irish Wolfhound, King Charles Spaniel, Labrador Retriever, Newfoundland, Old English Sheepdog, Papillon, Pekingese, Pointer, Pomeranian, Poodle, Pug, Rhodesian Ridgeback, Rottweiler, Schnauzer, Scottish Terrier, Shetland Sheepdog, Weimaraner, West Highland White Terrier, Whippet, White Shepherd and Yorkshire Terrier.

In addition we also supply a generic configuration for use with other breeds and which uses a breed-independant nomenclature for the expressed colors.

For background information on canine colour genetics please see our dog colour genetics primer.

Breeders Assistant for Cavies
Breeders Assistant for Rabbits
Breeders Assistant for Rats

A single, 'standard' configuration is supplied for these versions.

Breeders Assistant for Birds

Cockatiel, Zebra Finch.

Breeders Assistant for Hamsters

Syrian, Campbells.

These are supplied in text format as they were created by a user of the product who kindly gave permission for us to distribute them.

Breeders Assistant for Horses
Breeders Assistant (Generic)

These versions do not ship with any pre-configured genetic configurations.

Inheritance Probability Calculation

Gene Probability Calculations
Gene Probability Calculations

 

Gene Probability Analysis
Gene Probability Analysis

Breeders Assistant, Professional Edition, can predict the probability that an animal:

  • Is homozygous for a given allele (i.e. carries 2 copies of the same allele). E.g. for predicting whether a recessive trait is likely to be expressed.
  • Is heterozygous for a given allele (i.e. carries only 1 copy the given allele). E.g. for predicting whether an individual will be a carrier for a given recessive disease.
  • Is homozygous or heterozygous for a given allele (i.e. carries 1 or 2 copies the given allele). E.g. for predicting whether a dominant trait might be expressed.
  • Or, in the case of a polygenic trait, the mean (average) likely 'value'.

The calculation is done by examining the genotypes of a configurable number of generations of ancestors (max. 16).

It is possible to set 'background population probabilities' for individual polygenes and alleles. This is used in the calculation for any ancestor where the genotype is not stated.

The calculation can either be done for a specific animal in which case you get a detailed report for each gene covered, or it can be done for a set of animals in which case you get a report listing the animals in order of increasing or decreasing inheritance probability.

Gene Frequency Analysis

Gene Frequency Analysis
Gene Frequency Analysis

Breeders Assistant, Professional Edition, can create a report that analyses the distribution of genes and alleles within a population.

This is useful if you're using Breeders Assistant to record details of a 'population' - e.g. all members of a given breed in a region or country - as you can then analyse the distributions of the different alleles within that population.


1. Mating certificates are only available with the Cat and Dog versions of Breeders Assistant.


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