Video: Extended Edition: Founder Analysis - How To Compute Founder Equivalents, Contributions And Related Metrics
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This video demonstrates the computation of founder metrics including founder equivalents and founder genome equivalents for a breeding population using the Extended Edition.
This is also covered in the longer video 'Measures Of Genetic Diversity In Depth'
There is also a separate video which you are recommended to watch first that explains about the test data and how to set up a breeding pool.
1:00 | The test data | 5:32 | Founder alleles retained | 6:54 | Number of effective ancestors |
1:49 | About founders | 5:40 | Founder genome uniqueness | 7:33 | Individual founder contributions to members of the breeding pool |
4:20 | Computing founder metrics | 5:50 | Founder equivalents | 9:15 | Gene drop analysis |
5:25 | Founder contribution | 6:34 | Founder genome equivalents |
See Also: Inbreeding , Test Data And Defining The Breeding Pool , Ranking Prospective Matings In Depth , Measures Of Genetic Diversity In Depth , Ranking Matings By Inbreeding , Ranking Matings By Influence , Ranking Matings By Mean Kinship , Bulk Computation of Inbreeding etc. , Kinship Matrix , Computing Mean Kinships
For a full list of videos see the main videos page.
1. Founder equivalents and founder genome equivalents are computed using the method of Lacy, RC. ("Analysis of founder representation in pedigrees: Founder equivalents and founder genome equivalents". Zoo Biology 8:111-124, 1989.)
2. The number of effective ancestors is computed using the method of Boichard, D, Maignel L, and Verrier, E. ("The value of using probabilities of gene origin to measure genetic variability in a population". Genetics Selection Evolution, 1997; 29(1): 5-23.)
3. Gene drop analysis and genome uniqueness is described in MacCluer et al ("Pedigree analysis by computer simulation", Zoo Biology 5, 147/160, 1986).