Video: Extended Edition: Measures Of Genetic Diversity In Depth
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This video explains in detail the advanced population genetics reports of the Extended Edition - including bulk calculation of inbreeding and genome uniqueness, founder analysis including founder equivalents and founder genome equivalents, mean kinship computation and the calculation of the kinship/relationship matrix.
This is a long video - 20+ minutes. If you're interested in all of the advanced population genetics reports then this is the one to watch.
But if you're only interested only some, there are separate smaller videos you might prefer - see: bulk computation of inbreeding, genome uniqueness and pedigree completeness 
, how to display kinship/relationship matrix , computation of mean kinships for the breeding pool and founder analysis including computation of founder equivalents
There is also a separate video which you are recommended to watch first that explains about the test data and how to set up a breeding pool.
| 1:09 | The test data | 7:20 | Exporting results | 14:52 | Founder alleles retained |
| 1:47 | Computing key metrics - bulk computation of inbreeding, genome uniqueness and pedigree completeness | 7:29 | Information panel | 14:59 | Founder genome uniqueness |
| 3:38 | Pedigree completeness | 7:43 | Computing mean kinship | 15:13 | Founder equivalents |
| 3:57 | Ancestral inbreeding coefficient | 9:31 | Memory requirements when computing kinships | 15:51 | Founder genome equivalents |
| 4:07 | Genome uniqueness | 10:05 | Displaying the kinship matrix | 16:11 | Number of effective ancestors |
| 5:00 | Ordering the results | 11:37 | About founder analysis | 16:51 | Individual founder contributions to members of the breeding pool |
| 5:18 | Genome uniqueness 2 | 14:23 | Computing founder metrics | 18:59 | Gene drop analysis |
| 7:11 | Adjusting columns | 14:45 | Founder contribution |
See Also: Inbreeding , Test Data And Defining The Breeding Pool , Ranking Prospective Matings In Depth , Ranking Matings By Inbreeding , Ranking Matings By Influence , Ranking Matings By Mean Kinship , Bulk Computation of Inbreeding etc. , Kinship Matrix , Computing Mean Kinships , Founder Analysis
For a full list of videos see the main videos page.
1. The ancestral inbreeding coefficient is computed using the method of Ballou, JD. ("Ancestral Inbreeding Only Minimally Affects Inbreeding Depression in Mammalian Populations", Journal of Heredity 1997, 8:169-178).
2. The pedigree completeness index is computed using the method of MacCluer et al ("Inbreeding and Pedigree Structure in Standardbreed Horses", Journal of Heredity 1983, 74:394-399).
3. Founder equivalents and founder genome equivalents are computed using the method of Lacy, RC. ("Analysis of founder representation in pedigrees: Founder equivalents and founder genome equivalents". Zoo Biology 8:111-124, 1989.)
4. The number of effective ancestors is computed using the method of Boichard, D, Maignel L, and Verrier, E. ("The value of using probabilities of gene origin to measure genetic variability in a population". Genetics Selection Evolution, 1997; 29(1): 5-23.)
5. Fisher's reproductive value 'Vx' ("The Genetical Theory of Natural Selection". Fisher, R., 1930.)
6. Gene drop analysis and genome uniqueness is described in MacCluer et al ("Pedigree analysis by computer simulation", Zoo Biology 5, 147/160, 1986).